BIOTESYS supports publications and regularly PUBLISHES scientific articles on various topics

Read our publications on the testing and scientific validation of biological and chemical products here.

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Publi­cations

15. May 19

Dietary and lifestyle predictors of folate insufficiency in non-supplemented German women

Low folate status is a risk factor for birth defects. We studied concentrations of red blood cell (RBC)- and serum folate in 198 German women in relation to information on dietary folate intake, demographic and lifestyle factors.


Obeid R, Schön C, Wilhelm M, Pietrzik K, Pilz S

Int J Food Sci Nutr. 2019 May; 70(3):367-376. doi: 10.1080/09637486.2018.1511686. Epub 2018 Sep 7.

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24. April 19

Effects of an Oil-Free Hydroethanolic Pumpkin Seed Extract on Symptom Frequency and Severity in Men with Benign Prostatic Hyperplasia: A Pilot Study in Humans

Majority of men are affected by symptomatic benign prostatic hyperplasia (BPH) from a certain age. Botanical extracts are frequently used in the early management of the symptoms. In a single-arm, mono-centre pilot study, the effects of a proprietary oil-free hydroethanolic pumpkin seed extract on the symptoms of BPH were investigated.


Leibbrand M, Siefer S, Schön C, Perrinjaquet-Moccetti T, Kompek A, Csernich A, Bucar F, Heinrich Kreuter M

Journal of Medicinal Food. Published online 24 Apr 2019 doi.org/10.1089/jmf.2018.0106

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09. November 18

Bioavailability Study of Maqui Berry Extract in Healthy Subjects

Several health promoting effects have been reported for maqui berry, rich in anthocyanins. Direct effects of anthocyanins as well as bioactive metabolites might be involved. Within the study, bioavailability of a proprietary standardized maqui berry extract Delphinol® was investigated based on two selected anthocyanins (delphinidin-3-O-glucoside (DS) + cyanidin-3-O-sambubioside (CS)) and two breakdown products (protocatechuic acid (PCA) + gallic acid (GA)) after a single-dose supplementation in humans.


Schön C, Wacker R, Micka A, Steudle J, Lang S, Bonnländer B

Nutrients. 2018 Nov; 10(11): 1720. Published online 2018 Nov 9. doi: 10.3390/nu10111720

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10. September 18

Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomised, Placebo-Controlled Study in Healthy Subjects

Each year, adults suffer about two to four upper respiratory tract infections (URTIs), mostly in winter. The aim of the study was to evaluate the effects of brewers' yeast (1,3)-(1,6)-beta-glucan on incidence and severity of upper respiratory tract infections (URTIs).


Dharsono T, Rudnicka K, Wilhelm M, Schoen C

J Am Coll Nutr. 2018 Sep 10:1-11. doi: 10.1080/07315724.2018.1478339

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07. August 18

Blood glucose response after oral intake of lactulose in healthy volunteers: A randomized, controlled, cross-over study

Lactulose can be used as a functional food ingredient. During manufacturing as liquid or crystalline formulation, impurities with different sugars occur. Lactulose may also be consumed by people with impaired glucose tolerance, including diabetics. For these consumers, it is of interest whether the described carbohydrate impurities may increase blood glucose levels after ingestion. This study was performed to investigate possible changes of blood glucose levels after oral intake of 10 g and 20 g of liquid and crystalline lactulose in healthy subjects. The small amounts of carbohydrate impurities did not influence blood glucose levels, indicating potential applicability to people with impaired glucose tolerance.


Steudle J, Schön C, Wargenau M, Pauly L, Schwejda-Güttes S, Gaigg B, Kuchinka-Koch A, Stover JF

World J Gastrointest Pharmacol Ther. Aug 7, 2018; 9(3): 22-30 Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22

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09. June 18

Absorption of Hydroxytyrosol from Different Sources and its Impact on Lipid Status in Human Subjects

There is growing interest in the health effects of dietary polyphenols on cardiovascular risk factors. In this context, the effect of hydroxytyrosol on lipid status was investigated in healthy subjects. Hydroxytyrosol, a polyphenol especially known from olive oil, is available on the market from different sources. Absorption from those sources is prerequisite for its effects.


Siefer S, Wacker R, Wilhelm M, Schoen C

J Nutri Med Diet Care 4:025. doi.org/10.23937/2572-3278.1510025

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