Using mid infrared technology as new method for the determination of the dwell time of salivary substitutes on three dimensional gingiva models

Many people suffer from dry mouth (xerostomia) due to radiotherapy treatment of head and neck cancer, diseases like Sjogren's syndrome or as adverse effects to prescribed medications. Salivary substitute products like gels or sprays are often used for treatment. Efficacy of those oral care products are regularly assessed by validated or even not validated questionnaires. To determine the adhesion effect over time more objectively a new and sensitive method was established. The following study was designed to assess the dwell time of different oral care products in vitro.

Engelhart K, Popescu A, and Bernhardt J

BMC Ear Nose Throat Disord. 2016; 16: 6. Published online 2016 Mar 15. doi: 10.1186/s12901-016-0025-5