The Synergistic Antioxidate Effect of Ascorbyl 2-Phosphate and Alpha-Tocopheryl Acetate

The use of antioxidants in cosmetics has a long history. Two different modes of application can be distinguished. They are used either to stability the cosmetic formulation or to protect the skin. As a formulation stabiliser, they serve as a "technical antioxidant." Here they are being used to prevent the oxidative deterioration of labile ingredietns such as unsaturated fatty acids or oxidation-prone active ingredeitns. Both synthetic compounds like butylated hydroxytoluene and natural antioxidants like alpha-tocopherol are frequently used for this purpose. The synergistic antioxidant effect of ascorbyl 2-phosphate and alpha-tocopheryl acetate was investigated in vitro using a human keratinocyte cell line and a fluorescence-based assay system.

Jentzsche A, Streicher H, Engelhart K

Cosmetics & Toiletries, Nov. 4, 2011, 116[6], 55-64. 2011.