The effectiveness of daily supplementation with 400 or 800 µg/day folate in reaching protective red blood folate concentrations in non-pregnant women: a randomized trial

Folate required to achieve desirable red blood cell (RBC) folate concentrations within 4-8 weeks pre-pregnancy is not known. We studied the effect of supplementation with 400 or 800 µg/day folate in achieving RBC-folate ≥906 nmol/L.

Obeid R, Schön C, Wilhelm M, Pietrzik K, Pilz S

Eur J Nutr. 2018 Aug;57(5):1771-1780. doi: 10.1007/s00394-017-1461-8. Epub 2017 Apr 26.