3,4-Dihydroxymandelic acid, a noradrenalin metabolite with powerful antioxidative potential

The decarboxylated noradrenaline metabolite 3,4-dihydroxymandelic acid [DHMA, 2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid] occurs in different mammalian tissues, especially in the heart. To elucidate the physiological function of DHMA, the antioxidative and radical scavenging activity was determined by physicochemical and cell-based test systems.

Ley JP, Engelhart K, Bernhardt J, Bertram HJ

J Agric Food Chem. 2002 Oct 9; 50(21):5897-902.