Hormonal Contraceptive Use Is Associated With Higher Total but Unaltered Free 25-Hydroxyvitamin D Serum Concentrations

Intake of hormonal contraceptives (HC) is associated with higher total 25-hydroxyvitamin D [25(OH)D] concentrations, but the effect of HC on free 25(OH)D is unclear. We investigated whether free 25(OH)D concentrations differ according to use of HC.

Pilz S, Obeid R, Schwetz V, Trummer C, Pandis M, Lerchbaum E, Pieber TR, Obermayer-Pietsch B, Wilhelm M, Hahn A, Schön C

J Clin Endocrinol Metab. 2018 Jun 1;103(6):2385-2391. doi: 10.1210/jc.2018-00336.