MARK-AGE population: From the human model to new insights

Many relevant EU projects were funded during last decade and MARK-AGE (European Study to Establish Biomarkers of Human Ageing) was the first focused on the identification of biomarkers connecting itself with a previous funded project, i.e. GEHA (Genetic of Healthy Ageing) that identified European families with longevity component (Franceschi et al., 2007). MARK-AGE was mainly a cross sectional study, based on definite assumptions and focused on an age range between 34 and 75 years, in order to identify early biomarkers of biological vs. chronological age, potentially capable of predicting the rate of ageing later in life.

Miriam Capri, María Moreno-Villanueva, Elisa Cevenini, Elisa Pini, Maria Scurti, Vincenzo Borelli, Maria Giustina Palmas, Marco Zolid, Christiane Schön, Anne Siepelmeyer, Jürgen Bernhardt, Simone Fiegl, Gerben Zondag, Anton J.M. de Craen, Antti Hervonen, Mikko Hurme, Ewa Sikora, Efstathios S. Gonos, Claudio Franceschi