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Publi­kationen

23. July 19

Postprandial Effects of a Proprietary Milk Protein Hydrolysate Containing Bioactive Peptides in Prediabetic Subjects

Milk proteins have been hypothesized to protect against type 2 diabetes (T2DM) by beneficially modulating glycemic response, predominantly in the postprandial status. In the present study, the impact of a milk protein hydrolysate of native whey origin with alpha-glucosidase inhibiting properties was determined in prediabetics in a randomized, cross-over trial.


Sartorius T, Weidner A, Dharsono T, Boulier A, Wilhelm M, Schön C

Nutrients 2019, 11(7), 1700; https://doi.org/10.3390/nu11071700

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01. July 19

A liquid phospholipid formulation of a Curcumin extract with high concentration of phosphatidylcholine (PHOSAL® Curcumin) improves the transport of Curcuminoids across Caco-2 intestinal epithelial cells

The use of curcumin as dietary supplement to ameliorate inflammation, arthritis, stomach, skin, liver, and gallbladder problems, is hampered by the lack of oral absorption. In this study, an in vitro digestion method and Caco-2 cell-lines were used to assess the influence of the solubilisation of curcuminoids in a liquid formulation comprising a high content of phosphatidylcholine on the transport of the curcuminoids across a Caco-2 cell monolayer, compared to powdered curcuminoids.


Gebhardt P, van Hoogevest P, Engelhart-Jentzsch K

Agro FOOD Industry Hi Tech, 2019, vol. 30(4) July/August 2019

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15. May 19

Dietary and lifestyle predictors of folate insufficiency in non-supplemented German women

Low folate status is a risk factor for birth defects. We studied concentrations of red blood cell (RBC)- and serum folate in 198 German women in relation to information on dietary folate intake, demographic and lifestyle factors.


Obeid R, Schön C, Wilhelm M, Pietrzik K, Pilz S

Int J Food Sci Nutr. 2019 May; 70(3):367-376. doi: 10.1080/09637486.2018.1511686. Epub 2018 Sep 7.

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24. April 19

Effects of an Oil-Free Hydroethanolic Pumpkin Seed Extract on Symptom Frequency and Severity in Men with Benign Prostatic Hyperplasia: A Pilot Study in Humans

Majority of men are affected by symptomatic benign prostatic hyperplasia (BPH) from a certain age. Botanical extracts are frequently used in the early management of the symptoms. In a single-arm, mono-center pilot study, the effects of a proprietary oil-free hydroethanolic pumpkin seed extract on the symptoms of BPH were investigated.


Leibbrand M, Siefer S, Schön C, Perrinjaquet-Moccetti T, Kompek A, Csernich A, Bucar F, Heinrich Kreuter M

Journal of Medicinal Food. Published online 24 Apr 2019 doi.org/10.1089/jmf.2018.0106

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09. November 18

Bioavailability Study of Maqui Berry Extract in Healthy Subjects

Several health promoting effects have been reported for maqui berry, rich in anthocyanins. Direct effects of anthocyanins as well as bioactive metabolites might be involved. Within the study, bioavailability of a proprietary standardized maqui berry extract Delphinol® was investigated based on two selected anthocyanins (delphinidin-3-O-glucoside (DS) + cyanidin-3-O-sambubioside (CS)) and two breakdown products (protocatechuic acid (PCA) + gallic acid (GA)) after a single-dose supplementation in humans.


Schön C, Wacker R, Micka A, Steudle J, Lang S, Bonnländer B

Nutrients. 2018 Nov; 10(11): 1720. Published online 2018 Nov 9. doi: 10.3390/nu10111720

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10. September 18

Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects

Each year, adults suffer about two to four upper respiratory tract infections (URTIs), mostly in winter. The aim of the study was to evaluate the effects of brewers' yeast (1,3)-(1,6)-beta-glucan on incidence and severity of upper respiratory tract infections (URTIs).


Dharsono T, Rudnicka K, Wilhelm M, Schoen C

J Am Coll Nutr. 2018 Sep 10:1-11. doi: 10.1080/07315724.2018.1478339

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