The determination of potential genotoxic effects is an essential component of the safety assessment. Applying in vitro testing, a combination of tests is usually used to answer this complex question. Available here are a number of recognised protocols, as well as other standard methods for the measurement of DNA damage.
BioTeSys offers a specific test package for detecting the endpoints chromosome damage and DNA strand breaks. The test methods complement each other and can detect DNA double-strand breaks directly and indirectly.
To determine the cellular toxicity, we offer the in vitro methods:
For further information please see our fact sheets on
Genotoxicity testing (Download 986 KB)
Automated GENOTOX-Assay with 3D-skin models (Download 652 KB)
An EU project to make the use of nanomaterials safer for everyone. BioTeSys is part of an EU-wide consortium for the specification of toxicological properties of nanoparticles